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Image Search Results


Stepwise Minimum Objective Function Changes for  Linear Mixed‐Effects Model  for the Dependent Variables ΔΔQTc, ΔΔQTcF, or ΔΔQTcP

Journal: Journal of Clinical Pharmacology

Article Title: Linear mixed‐effects model of QTc prolongation for olmesartan medoxomil

doi: 10.1002/jcph.572

Figure Lengend Snippet: Stepwise Minimum Objective Function Changes for Linear Mixed‐Effects Model for the Dependent Variables ΔΔQTc, ΔΔQTcF, or ΔΔQTcP

Article Snippet: Linear regression models for olmesartan plasma concentrations and ΔΔQTc were assessed for the 2 olmesartan treatments using a linear mixed‐effects model in NONMEM (version 7.1.0; ICON plc, Ellicott City, Maryland).

Techniques:

Parameter Estimates for the  Linear Mixed‐Effects Model  for the Effect of Olmesartan Plasma Concentrations (OM conc ) and Baseline‐Corrected, Placebo‐Adjusted Heart Rate (ΔΔRR) on ΔΔQTc

Journal: Journal of Clinical Pharmacology

Article Title: Linear mixed‐effects model of QTc prolongation for olmesartan medoxomil

doi: 10.1002/jcph.572

Figure Lengend Snippet: Parameter Estimates for the Linear Mixed‐Effects Model for the Effect of Olmesartan Plasma Concentrations (OM conc ) and Baseline‐Corrected, Placebo‐Adjusted Heart Rate (ΔΔRR) on ΔΔQTc

Article Snippet: Linear regression models for olmesartan plasma concentrations and ΔΔQTc were assessed for the 2 olmesartan treatments using a linear mixed‐effects model in NONMEM (version 7.1.0; ICON plc, Ellicott City, Maryland).

Techniques: Clinical Proteomics